Snakes on a Plane (2006)
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An FBI agent takes on a plane full of deadly and poisonous snakes, deliberately released to kill a witness being flown from Honolulu to Los Angeles to testify against a mob boss.
Director: David R. Ellis
Writers: John Heffernan (screenplay), Sebastian Gutierrez (screenplay)
Stars: Samuel L. Jackson, Julianna Margulies and Nathan Phillips